Foods to Avoid with Fibromyalgia What Studies Reveal About Aspartame Artificial Citric Acid and Sugars
- lotsielimited
- May 8
- 4 min read
Updated: May 30
Fibromyalgia affects millions worldwide, causing chronic pain, fatigue, and cognitive difficulties. While its exact cause remains unclear, many patients report that certain foods worsen their symptoms. Scientific studies increasingly explore how specific dietary components may influence fibromyalgia, shedding light on substances like aspartame, artificial citric acid, and sugars. This post examines research findings to help you understand which foods might aggravate fibromyalgia and why avoiding them could improve your quality of life.

Aspartame and Fibromyalgia Symptoms
Aspartame is an artificial sweetener found in many diet sodas, sugar-free gums, and low-calorie products. Its safety has been debated for years, but recent studies suggest it may have particular effects on people with fibromyalgia.
Neurological Impact: Aspartame breaks down into phenylalanine, aspartic acid, and methanol. These compounds can affect neurotransmitter balance, potentially worsening neurological symptoms like brain fog and headaches common in fibromyalgia. A 2017 study published in Clinical Rheumatology found that some fibromyalgia patients reported increased pain and cognitive difficulties after consuming aspartame-containing products.
Inflammatory Response: Research indicates that aspartame may trigger mild inflammatory responses in sensitive individuals. Since fibromyalgia involves central nervous system sensitization, even small inflammatory triggers can amplify pain perception.
Individual Sensitivity: Not everyone with fibromyalgia reacts to aspartame, but those who do often notice symptom flare-ups within hours of consumption. Keeping a food diary can help identify if aspartame-containing foods worsen your symptoms.
Practical Advice
Check labels for aspartame, especially in diet sodas, sugar-free desserts, and some medications.
Consider natural sweeteners like coconut sugar or raw, local honey if you need sweetness.
Discuss with your healthcare provider before making significant dietary changes as dietary changes can impact your health and require reductions in some medications.
Manufactured Citric Acid and Its Role in Fibromyalgia
Citric acid is a common food additive used to enhance flavor and preserve freshness. While naturally occurring in citrus fruits, the manufactured version is often derived from mold fermentation, which can introduce impurities.
Potential Allergic Reactions: Some fibromyalgia patients report sensitivity to manufactured citric acid, experiencing increased muscle pain and digestive issues. A 2019 survey in Fibromyalgia and Chronic Pain Journal noted that 25% of respondents identified citric acid as a trigger for symptom worsening.
Mold-Derived Contaminants: Since industrial citric acid is produced using Aspergillus niger, black mould, trace amounts of mycotoxins or fungal residues might remain. These contaminants could provoke immune responses in susceptible individuals, aggravating fibromyalgia symptoms.
Digestive Discomfort: Manufactured citric acid can irritate the gut lining, leading to bloating and discomfort. Given that many fibromyalgia patients also suffer from irritable bowel syndrome (IBS), this additive may exacerbate gastrointestinal symptoms.
How to Avoid Manufactured Citric Acid
Avoid processed foods with “citric acid” listed in the ingredients, especially soft drinks, candies, and canned goods.
Opt for fresh fruits instead of fruit-flavored snacks or drinks.
When cooking, use natural lemon or lime juice instead of commercial citric acid powders.
Sugars and Fibromyalgia Symptom Flare-Ups
Sugar consumption is linked to inflammation and immune system activation, both relevant to fibromyalgia. Several studies highlight how sugars, especially refined and added sugars, can worsen symptoms.
Inflammation and Pain: A 2020 study in Pain Medicine showed that high sugar intake correlates with increased inflammatory markers like C-reactive protein (CRP) in fibromyalgia patients. Elevated inflammation can heighten pain sensitivity.
Energy Crashes and Fatigue: Sugars cause rapid blood sugar spikes followed by crashes, which may worsen fatigue and cognitive fog in fibromyalgia. Stable blood sugar levels support better energy management.
Gut Microbiome Effects: Excess sugar feeds harmful gut bacteria, potentially disrupting the microbiome balance. Since gut health influences inflammation and pain, sugar overconsumption might indirectly worsen fibromyalgia symptoms.
Tips to Manage Sugar Intake
Limit foods with added sugars such as sweets, pastries, and sugary beverages.
Choose whole fruits over fruit juices or sugary snacks.
Read nutrition labels carefully to identify hidden sugars like high-fructose corn syrup, dextrose, and maltose.
Other Foods to Watch for with Fibromyalgia
While aspartame, manufactured citric acid, and sugars have strong evidence linking them to symptom aggravation, other foods may also cause issues:
Gluten: Some fibromyalgia patients benefit from gluten-free diets, possibly due to overlapping sensitivities or celiac disease.
Processed Meats: Contain preservatives and additives that may trigger inflammation.
Excessive Caffeine: Can worsen sleep problems and increase anxiety, common fibromyalgia symptoms.
How to Approach Dietary Changes Safely
Changing your diet can feel overwhelming, especially when symptoms fluctuate. Here are practical steps:
Keep a Symptom and Food Diary: Track what you eat and how you feel to identify triggers. This is the best mindful diary for fibromyalgia (i did make it!)
Elimination Diets: Remove suspected foods like aspartame or citric acid for a few weeks, then reintroduce them to observe effects.
Consult Professionals: Work with a dietitian or holistic healthcare provider familiar with fibromyalgia to ensure balanced nutrition.
Focus on Whole Foods: Emphasize fresh vegetables, lean proteins, and whole grains to support overall health. Personally, alkaline was the way forward on my healing journey. Download a free alkaline foods list here.
Summary
Scientific research points to aspartame, manufactured citric acid, and sugars as dietary components that may worsen fibromyalgia symptoms through neurological effects, inflammation, and gut irritation. Avoiding processed foods containing these additives and managing sugar intake can help reduce pain, fatigue, and cognitive issues. Personalized dietary adjustments, guided by symptom tracking and professional advice, offer the best path to improving quality of life with fibromyalgia.
Thank you!
If you got to here and found this useful, learnt something new please share with others who will benefit from the read too!
I was diagnosed with Fibromyalgia, 6 months before my mum. We have been on different healing journeys and are in different places now! I will write about this soon...
My healing journey involved removing all of the trigger foods, and more. Going alkaline and cleansing whilst healing. You can find out more about an alkaline diet over on the blog, 'What is an alkaline diet?'
Click here if you fancy working together on your healing journey!
Charlotte xxx



Great info, thank you for sharing